HOUSTON - Two people were killed and at least 29 others injured after a tornado caused significant damage Saturday night in the region of Oklahoma City, US state of Oklahoma, local media reported Sunday.

The storm leveled a motel, and left a lengthy path of rubble and debris as it hit El Reno, about 40 km west of Oklahoma City, the capital city of the state, media reports showed.

"It's a pretty devastating sight," Mayor of El Reno Matt White told a news conference on Sunday. "It is very traumatic."

The mayor said that officials were working to notify relatives of the two victims.

The twister touched down in El Reno on Saturday night as a powerful storm system rolled through the state of Oklahoma. A search-and-rescue operation was underway Sunday morning.